|
|||||
|
|
Mechanistic View of hnRNPA2 Low-Complexity Domain Structure,Interactions, and Phase Separation Altered by Mutation and Arginine Methylation |
|
| Authors: | Veronica H Ryan Gregory L Dignon Gül H Zerze Charlene V Chabata Rute Silva Alexander E Conicella Joshua Amaya Kathleen A Burke Jeetain Mittal Nicolas L Fawzi |
| Institution: | 1. Neuroscience Graduate Program, Brown University, Providence, RI 02912, USA;2. Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA;3. Graduate Program in Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI 02912, USA;4. Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA 18015, USA |
| Abstract: |  |
| Keywords: | liquid-liquid phase separation RNP granule protein aggregation amyotrophic lateral sclerosis frontotemporal dementia inclusion body myopathy solution NMR spectroscopy protein interactions intrinsically disordered protein molecular dynamics simulation |
| 本文献已被 ScienceDirect 等数据库收录！ | |