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The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
Authors:Lingtao Jin  Jaemoo Chun  Chaoyun Pan  Avi Kumar  Guojing Zhang  Youna Ha  Dan Li  Gina N. Alesi  Yibin Kang  Lu Zhou  Wen-Mei Yu  Kelly R. Magliocca  Fadlo R. Khuri  Cheng-Kui Qu  Christian Metallo  Taofeek K. Owonikoko  Sumin Kang
Affiliation:1. Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA 30322, USA;2. Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA;3. Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA;4. School of Pharmacy, Fudan University, Shanghai 201203, China;5. Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA;6. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Abstract:
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  • Keywords:GLUD1  anoikis  metastasis  CamKK2  AMPKa  LKB1 deficient
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