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Protein Dynamics in Complex DNA Lesions
Authors:Radoslav Aleksandrov  Anton Dotchev  Ina Poser  Dragomir Krastev  Georgi Georgiev  Greta Panova  Yordan Babukov  Georgi Danovski  Teodora Dyankova  Lars Hubatsch  Aneliya Ivanova  Aleksandar Atemin  Marina N. Nedelcheva-Veleva  Susanne Hasse  Mihail Sarov  Frank Buchholz  Anthony A. Hyman  Stephan W. Grill  Stoyno S. Stoynov
Affiliation:1. Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str. Bl.21, 1113 Sofia, Bulgaria;2. Max Planck Institute for Molecular Cell Biology and Genetics, 108 Pfotenhauerstr., 01307 Dresden, Germany;3. Faculty of Mathematics and Informatics, Sofia University, St. Kliment Ohridski, 5 James Bourchier Blvd., 1164 Sofia, Bulgaria;4. Department of Mathematics, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104, USA;5. Medical Systems Biology, UCC, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstr. 74, 01307 Dresden, Germany
Abstract:
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  • Keywords:DNA repair dynamics  mathematical modeling  DNA damage tolerance  translesion synthesis  DSB repair  BER  NER  PARP inhibition  anticancer drug evaluation  live-cell imaging
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