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PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Double-Strand Break Formation at Its Binding Sites |
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| Authors: | Boubou Diagouraga Julie AJ Clément Laurent Duret Jan Kadlec Bernard de Massy Frédéric Baudat |
| Institution: | 1. IGH, CNRS, Université Montpellier, Montpellier, France;2. Université de Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Evolutive UMR 5558, Villeurbanne, France;3. Université Grenoble Alpes, CNRS, CEA, IBS, F-38000 Grenoble, France |
| Abstract: |  |
| Keywords: | DNA double-strand break PRDM9 DMC1 histone methylation meiosis homologous recombination H3K4me3 H3K36me3 recombination hotspot chromatin |
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