Aluminium in the brain and heart of the rainbow trout |
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| Authors: | C. Exley |
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| Affiliation: | Centre for Inorganic Chemistry and Materials Science, Department of Chemistry, Keele University, Staffordshire ST5 5BG, U.K. |
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| Abstract: | Tissue residue analysis and aluminium-specific hifstochemistry demonstrated that the chronic exposure of rainbow trout to aluminium results in the systemic accumulation of aluminium and a distinct neuropathology in the brain. Aluminium was found associated with endothelial and epithelial surfaces including the cerebrovascular endothelium of the brain and the endothelium of the bulbus arteriosus of the heart. The potential for aluminium to compromise the barrier properties of membranes may underlie its known toxicity in fish. |
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| Keywords: | aluminium chronic toxicity freshwater fish neurodegenerative disease |
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