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Effect of acid metabolites on the osteoinductive activity of the bone matrix |
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| Authors: | D D Sumarokov A Kh Shamsudinov M B Shvyrkov S L Siziakov |
| Abstract: | The osteoinductive activity of bone matrix demineralized in acid metabolites of glycolysis and Krebs cycle have been studied in rats. The highest osteoinductive effect was reached during the demineralization in oxaloacetic acid, the lowest one--in the malic acid. The regulatory role of glycolysis metabolites and Krebs Cycle in posttraumatic osteogenesis is under discussion. |
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