1.Laboratório de Biologia Molecular, Instituto de Ciências Biológicas,Universidade Federal de Goiás,Goiania,Brazil;2.Laboratório de Intera??o Parasito-Hospedeiro, Faculdade de Medicina,Universidade de Brasília,Brasília,Brazil
Abstract:
Background
Paracoccidioides brasiliensis is a thermodimorphic fungus, the causative agent of paracoccidioidomycosis (PCM). Serine proteases are widely distributed and this class of peptidase has been related to pathogenesis and nitrogen starvation in pathogenic fungi.