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Thermosensitive cell growth and permeability coded by an Rts1 plasmid and their suppression upon integration into the chromosome in Escherichia coli.
Authors:M Yoshikawa
Affiliation:Institute of Medical Science, University of Tokyo, Shiroganedai, Minato-ku, Tokyo, 108, Japan
Abstract:A multiphenotypically thermosensitive plasmid, Rts1, was found to confer upon the host cell of Escherichiacoli K12 an increased permeability through the cell surface to Actinomycin D and rifampicin as well as a detrimental host cell growth at 42°C only when it existed autonomously but not in an integrated state.
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