Biotransformation of ellipticine into 5-formyl ellipticine by Choisya ternata strains |
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Authors: | K. Kouadio M. Rideau C. Ganser J. C. Chénieux C. Viel |
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Affiliation: | (1) Faculté de Pharmacie, Laboratoire de Biotechnologie Végétale, F-37032 Tours, France;(2) ERA-CNRS 317, Faculté de Pharmacie, F-92190 Châtenay-Malabry, France |
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Abstract: | Sixteen Choisya ternata strains of same genotypic origin were examined for their capacities to biotransform ellipticine. Four strains were able to convert the drug into 5-formylellipticine with good yields. The reaction occurred only in agar medium and was different from ellipticine bioconversion by microorganisms or mammals. |
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