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Biotransformation of ellipticine into 5-formyl ellipticine by Choisya ternata strains
Authors:K. Kouadio  M. Rideau  C. Ganser  J. C. Chénieux  C. Viel
Affiliation:(1) Faculté de Pharmacie, Laboratoire de Biotechnologie Végétale, F-37032 Tours, France;(2) ERA-CNRS 317, Faculté de Pharmacie, F-92190 Châtenay-Malabry, France
Abstract:Sixteen Choisya ternata strains of same genotypic origin were examined for their capacities to biotransform ellipticine. Four strains were able to convert the drug into 5-formylellipticine with good yields. The reaction occurred only in agar medium and was different from ellipticine bioconversion by microorganisms or mammals.
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