Subgroups of older adults with osteoarthritis based upon differing comorbid symptom presentations and potential underlying pain mechanisms |
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| Authors: | Susan L Murphy Angela K Lyden Kristine Phillips Daniel J Clauw David A Williams |
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| Institution: | (1) Department of Physical Medicine and Rehabilitation, University of Michigan, 300 North Ingalls, 9th floor, Ann Arbor, MI 48109-2007, USA;(2) Geriatric Research, Education and Clinical Center (GRECC), Veterans Affairs Ann Arbor Health Care System, Michigan, 2215 Fuller Rd, Ann Arbor, MI 48105, USA;(3) Division of Rheumatology, Department of Internal Medicine, University of Michigan, Domino’s Farms, 24 Frank Lloyd Wright Drive, Lobby M, Ann Arbor, MI 48105-5737, USA;(4) Departments of Anesthesiology and Psychiatry, University of Michigan, Domino’s Farms, 24 Frank Lloyd Wright Drive, Lobby M, Ann Arbor, MI 48105-5737, USA;(5) Department of Psychology, University of Michigan, Domino’s Farms, 24 Frank Lloyd Wright Drive, Lobby M, Ann Arbor, MI 48105-5737, USA |
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| Abstract: | Introduction Although people with knee and hip osteoarthritis (OA) seek treatment because of pain, many of these individuals have commonly
co-occurring symptoms (for example, fatigue, sleep problems, mood disorders). The purpose of this study was to characterize
adults with OA by identifying subgroups with the above comorbid symptoms along with illness burden (a composite measure of
somatic symptoms) to begin to examine whether subsets may have differing underlying pain mechanisms. |
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