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Quantification of the whole-body burden of radiographic osteoarthritis using factor analysis
Authors:Amanda E Nelson  Robert F DeVellis  Jordan B Renner  Todd A Schwartz  Philip G Conaghan  Virginia B Kraus  Joanne M Jordan
Institution:(1) Thurston Arthritis Research Center, University of North Carolina, 3300 Thurston Building CB 7280, Chapel Hill, NC 27599, USA;(2) Department of Health Behavior and Health Education, Gillings School of Global Public Health, University of North Carolina, 302 Rosenau Hall, Chapel Hill, NC 27599, USA;(3) Department of Radiology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC 27514, USA;(4) Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, 3106E McGavran-Greenberg Hall, Chapel Hill, NC 27599, USA;(5) Section of Musculoskeletal Disease, University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Chapeltown Road, Leeds, LS7 4SA, UK;(6) Department of Medicine, Duke University Medical Center, 595 La Salle St, Durham, NC 27710, USA
Abstract:

Introduction  

Although osteoarthritis (OA) commonly involves multiple joints, no widely accepted method for quantifying whole-body OA burden exists. Therefore, our aim was to apply factor analytic methods to radiographic OA (rOA) grades across multiple joint sites, representing both presence and severity, to quantify the burden of rOA.
Keywords:Radiography  osteoarthritis  factor analysis
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