Evidence of the presence of GTPase inhibiting proteins for a low M(r) GTP-binding protein, ram p25, in rat spleen and pheochromocytoma PC12 cells. |
| |
| Authors: | K Nagata T Suzuki Y Okano Y Nozawa |
| |
| Affiliation: | Department of Biochemistry, Gifu University School of Medicine, Japan. |
| |
| Abstract: | 1. GTPase inhibiting activity for a low M(r) GTP-binding protein, ram p25, was detected in the cytosolic fractions of rat spleen and PC12 cells. 2. The inhibitors were heat-labile and trypsin-sensitive, indicating that they were of proteinous nature. 3. The molecular mass of the inhibitor in the spleen appeared to be about 65 kDa on the elution profile from the gel filtration column. |
| |
| Keywords: | |
|
|
