A low molecular weight calf pineal peptide with an inhibiting effect on the growth of L1210 and HL60 cells. |
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Authors: | C Petrelli P Moretti F Petrelli M Bramucci |
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Affiliation: | Department of Molecular, Cellular and Animal Biology, University of Camerino, Italy. |
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Abstract: | The peptide isolated by us from calf pineal gland causes a reduction of RNA synthesis in vitro in L1210 and HL60 tumoral cells. This peptide also causes inhibition of cell proliferation; the cell viability is not modified. The effects are dose-dependent and reversible. |
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