Changes of glucocorticoid level in plasma and adrenal glands of pregnant rats and their offspring after antenatal stress of different etiology |
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| Authors: | L K Trofimova A A Baizhumanov E N Goncharenko Ya V Krushinskaya N A Sokolova N Yu Kudryashova |
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| Institution: | 1.Biological Faculty, Human and Animal Physiology Department,Moscow State University,Moscow,Russia |
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| Abstract: | We investigated the glucocorticoid level in plasma and adrenal glands of pregnant rats in the period of early organogenesis.
Tests were performed 24 hours after stress of different etiology (acute hypobaric hypoxia, intermittent normobaric hypoxia,
and immobilization) and then repeated in the adult offspring. There was a significant decrease in the glucocorticoid level
in pregnant rats 24 hours after hypoxic stress. Various changes of the basal glucocorticoid level were found in the offspring
after antenatal stress. Changes were mostly found in female offspring. |
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