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Study of stability mechanisms of embryonic development in fruit fly Drosophila
Authors:S. Yu. Surkova  V. V. Gurskiy  J. Reinitz  M. G. Samsonova
Affiliation:1.Department of Computational Biology, Center for Advanced Studies,St. Petersburg State Polytechnical University,St. Petersburg,Russia;2.Physico-Technical Institute,Russian Academy of Sciences,St. Petersburg,Russia;3.University of Chicago,Chicago,USA
Abstract:Living organisms well adapt themselves to changes in the environment and are robust to potential damage such as mutations. The epigenetic mechanism whereby the suppression of phenotypic variation is achieved has been called canalization. This paper summarizes results of research that employed experimental and theoretical approaches to uncover the mechanisms of canalization of variation in expression of segmentation genes.
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