Genetic variation of three autosomal STR Loci D21S1435, D21S1411, and D21S1412 in Korean population |
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| Authors: | Moon-Hee Lee So-Yeon Park Do-Jin Kim Mi-Jin Kim Hyun-Mee Ryu Youl-Hee Cho |
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| Institution: | (1) Laboratory of Medical Genetics, Cheil General Hospital and Women’s Healthcare Center, Kwandong University College of Medicine, Seoul, Korea;(2) Department of Obstetrics and Gynecology, Cheil General Hospital and Women’s Healthcare Center, Kwandong University College of Medicine, 1-19, Mookjung-dong, Chung-gu, Seoul, 100-380, Korea;(3) Department of Medical Genetics, College of Medicine, Hanyang University, 17, Haengdang-dong, Chung-gu, Seoul, 133-791, Korea; |
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| Abstract: | The autosomal tetranucleotide short tandem repeat loci D21S1435, D21S1411 and D21S1412 were analyzed in samples of unrelated
200 Korean individuals. The loci showed no significant deviations from Hardy–Weinberg equilibrium. Alleles were assigned according
to the International Society for Forensic Haemogenetics (ISFH) recommendations. The power of discrimination of the analyzed
markers was found to be high for the populations, thereby facilitating the validation and efficiency of these STR markers
in forensic human identification and paternity testing. To our knowledge, this is the first report of the nomenclature and
the allele frequency data for these three STR loci in Korean population. |
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