Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression |
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| Authors: | Dejonckheere Eline Vandenbroucke Roosmarijn E Libert Claude |
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| Institution: | Department for Molecular Biomedical Research, VIB, Ghent, Belgium. |
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| Abstract: | The predominant role of matrix metalloproteinase 8 in extracellular matrix turnover, modulation of inflammatory responses and other physiological processes is well documented. Several recent studies highlight the involvement of MMP8 in a wide range of pathologies. This review will shed light on the putative role of MMP8 as a drug target or disease marker in some inflammatory disorders and in cancer progression. |
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