Characterization of phospholipids in membrane vesicles derived from Pseudomonas aeruginosa |
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Authors: | Tashiro Yosuke Inagaki Aya Shimizu Motoyuki Ichikawa Sosaku Takaya Naoki Nakajima-Kambe Toshiaki Uchiyama Hiroo Nomura Nobuhiko |
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Affiliation: | Graduate School of Life and Environmental Sciences, University of Tsukuba, Ibaraki, Japan. |
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Abstract: | Many Gram-negative bacteria release membrane vesicles (MVs), but their phospholipid properties are poorly understood. Phosphatidylglycerol was present at high levels in MVs derived from Pseudomonas aeruginosa, but not in the cellular outer membrane. The ratio of stearic acid in MVs was high compared to that in the cellular outer membrane. These findings suggest that membrane rigidity is associated with MV biogenesis. |
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