Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula |
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| Authors: | Tan Lik Tong Chang Ying Yan Ashootosh Tripathi |
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| Institution: | National Institute of Education, Nanyang Technological University, 1 Nanyang Walk, Singapore, Singapore. LikTong.Tan@nie.edu.sg |
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| Abstract: | Besarhanamides A (1) and B (2) are fatty acid amides purified from the marine cyanobacterium, Lyngbya majuscula, collected from Pulau Hantu, Singapore. The structure determination of these secondary metabolites was carried out using extensive 2D NMR spectral data as well as chemical manipulations including the Marfey's method. In addition, besarhanamide A exhibited moderate toxicity with LD(50) at 13 microM in the brine shrimp toxicity bioassay. |
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| Keywords: | Lyngbya majuscula Oscillatoriaceae Cyanobacteria Brine shrimp toxicity Fatty acid amides Besarhanamides |
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