Identification of the origin of triploidy by HLA markers |
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| Authors: | P Couillin J Hors J Boué A Boué |
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| Institution: | (1) Groupe de Recherches de Biologie prénatale, INSERM (U 73), Château de Longchamp, F-75016 Paris, France;(2) Groupe de Recherches d'Immunogénétique de la Transplantation humaine, INSERM (U 93), Hôpital Saint-Louis, F-75475 Paris Cedex 10, France |
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| Abstract: | Summary HLA-A and HLA-B markers have been determined in fibroblasts grown from tissues of triploid conceptuses and have been tested in the parents. Informative data on the origin of triploidy were obtained in eight cases: diandry I or dispermy in 4 cases, diandry II or dispermy in 2, digyny I or II in 2. This confirms that triploidy involved more frequently two sets of paternal chromosomes. |
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