Genes involved in the development of the peripheral nervous system of Drosophila |
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Authors: | A Giangrande J Palka |
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Affiliation: | Department of Zoology, University of Washington, Seattle 98195. |
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Abstract: | The development of the peripheral nervous system (PNS) requires the activity of a number of genes. The neurogenic and the proneural genes are necessary in the earliest phase; their mutations lead to hyperplasia and partial or total elimination of the PNS respectively. Some of these mutations also affect other developmental processes. Other mutations affect later events: cut transforms one type of sensory organ into another; numb alters the fate of the components of a single sensory organ. We will describe the effects of the best studied mutations on PNS development and discuss the possible role of the wild type genes. |
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