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Effects of binding three lysine-rich H1-type histones to DNA and poly(dG-dC) |
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| Authors: | Elio Russo Vincenzo Giancotti Colyn Crane-Robinson |
| Institution: | Istituto di Chimica, Universitá degli Studi di Trieste, Piazzale Europa 1, 34127, Trieste, Italy Biophysics Laboratories, Portsmouth Polytechnic, Portsmouth, Hampshire PO1 2DT, UK |
| Abstract: | The degree of distortion of the B-form of DNA induced by the binding of the lysine-rich H1 histones is a function of the arginine content of the protein. Lysine-rich H1 histones do not induce the formation of the Z-form of poly(dG-dC) but, when they are bound to this polynucleotide in the B-form, the transition to the Z-form induced by Tb3+ is faster. |
| Keywords: | DNA histones Z-form poly(dG-dC) circular dichroism |
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