Expression of the PI4P 5-kinase Drosophila homologue skittles in the germline suggests a role in spermatogenesis and oogenesis |
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Authors: | Stefan Knirr Ansgar Santel R Renkawitz-Pohl |
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Institution: | Zoologie, Entwicklungsbiologie, FB Biologie, Philipps-Universit?t, Karl-von-Frisch-Strasse, 35032 Marburg, Germany, DE
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Abstract: | We have isolated the Drosophila gene skittles (sktl) which shows homology to members of a novel family of phosphatidylinositol-4-phosphate 5-kinases, including the gene product
encoded by the human STM-7.I gene which has been assigned to the neurodegenerative disorder Friedreichs ataxia. In situ hybridization
reveals sktl expression during oogenesis and spermatogenesis.
Received: 7 February1997 / Accepted: 4 April 1997 |
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Keywords: | Drosophila PIP2 Oogenesis Spermatogenesis Friedreichs ataxia |
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