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Expression of the PI4P 5-kinase Drosophila homologue skittles in the germline suggests a role in spermatogenesis and oogenesis
Authors:Stefan Knirr  Ansgar Santel  R Renkawitz-Pohl
Institution:Zoologie, Entwicklungsbiologie, FB Biologie, Philipps-Universit?t, Karl-von-Frisch-Strasse, 35032 Marburg, Germany, DE
Abstract: We have isolated the Drosophila gene skittles (sktl) which shows homology to members of a novel family of phosphatidylinositol-4-phosphate 5-kinases, including the gene product encoded by the human STM-7.I gene which has been assigned to the neurodegenerative disorder Friedreichs ataxia. In situ hybridization reveals sktl expression during oogenesis and spermatogenesis. Received: 7 February1997 / Accepted: 4 April 1997
Keywords:  Drosophila  PIP2  Oogenesis  Spermatogenesis  Friedreichs ataxia
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