Chemical ligation to obtain proteins comprising helices with individual amino acid sequences |
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| Authors: | Futaki S Aoki M Ishikawa T Kondo F Asahara T Niwa M Nakaya Y Yagami T Kitagawa K |
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| Affiliation: | Institute for Medicinal Resources, The University of Tokushima, Japan. futaki@scl.kyoto-u.ac.jp |
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| Abstract: | Development of the strategies for assembling multiple kinds of peptide segments would give new possibilities for the de novo design of functional proteins. We will introduce our approach for the selective assembly of helical peptide segments on a peptide template to give four-helix-bundle proteins comprising individual helices. |
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