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Does ‘Immortal DNA strand' exist in ‘immortal' stem cells?
作者姓名:Li  L
作者单位:Stowers Institute for Medical Research, Kansas City, MO 64110, USA.
摘    要:Stem cells function to generate differentiated cells, and, at the same time, are maintained as ‘immortal' cells through self-renewal. Accumulated evidence indicates that adult stem cells may be the most common precursor for cancers in adult mammalian tissue , and this concept is gaining increasing support . Meanwhile, this also raises the question of how stem cells, which have a much longer lifespan compared to other progenitor and mature cells, can avoid accumulating mutations from DNA replication errors, thereby reducing the risk of tumorigenesis.第一段]

关 键 词:干细胞  DNA  成熟细胞  细胞突变
本文献已被 维普 PubMed 等数据库收录!
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