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Determination of Knockdown Resistance (kdr) Allele Frequencies (T929I mutation) in Head Louse Populations from Mexico,Canada, and Peru
Authors:Gustavo Ponce-Garcia  Olga K. Villanueva-Segura  Karina Garza-Elizondo  Heriberto M. Villegas-Ramirez  Ildefonso Fernandez-Salas  Iram P. Rodriguez-Sanchez  Felipe Dzul-Manzanilla  Adriana E. Flores-Suarez
Affiliation:Universidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Laboratorio de Entomología Medica, San Nicolás de los Garza, N.L., 66455, México
Abstract:The head louse Pediculus humanus capitis (De Geer) is a hematophagous ectoparasite that inhabits the human scalp. The infestations are asymptomatic; however, skin irritation from scratching occasionally may cause secondary bacterial infections. The present study determined the presence and frequency of the knockdown resistance (kdr) mutation T929I in 245 head lice collected from Mexico, Peru, and Canada. Head lice were collected manually using a comb in the private head lice control clinic. Allele mutation at T9291 was present in 100% of the total sampled populations (245 lice) examined. In addition, 4.89% of the lice were homozygous susceptible, whereas 6.93% heterozygous and 88.16% homozygous were resistant, respectively. This represents the second report in Mexico and Quebec and fist in Lima.
Keywords:Pediculus humanus capitis   kdr   T929I
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