| 灵芝三萜酸分批发酵的非结构动力学模型 |
| |
| 引用本文： | 王晓玲,赵艳,刘高强,旷思敏.灵芝三萜酸分批发酵的非结构动力学模型[J].菌物学报,2011,30(5):767-773. |
| |
| 作者姓名： | 王晓玲 赵艳 刘高强 旷思敏 |
| |
| 作者单位： | 中南林业科技大学生命科学与技术学院林业生物技术湖南省重点实验室 长沙410004 |
| |
| 基金项目： | 教育部高校博士点基金（No. 20094321120003）；湖南省研究生科研创新基金（No. CX2010B315） |
| |
| 摘 要： | 研究了灵芝胞内和胞外三萜酸在30L发酵罐中分批发酵的动力学特征。利用Sigmoid函数构建了灵芝细胞生长、底物消耗、胞内和胞外三萜酸的非结构动力学模型，并根据Boltzmann拟合求解出各模型参数。结果表明，各模型预测值能够较好地吻合实验实测值。灵芝细胞比生长速率在第2.5天达到最大值（μmax），为0.700d?1；葡萄糖比消耗速率在第2.4天达到最大值（qS, max）为1.060d?1；胞内三萜酸比合成速率在第4.7天达到最大值（qITA, max）为11.345mg/(g·d)；胞外三萜酸比合成速
|
| 关 键 词： | 药用真菌 灵芝 深层发酵 三萜酸 动力学模型 |
Unstructured kinetic models for triterpene acids of Ganoderma lucidum in batch fermentation |
| |
| Authors: | WANG Xiao-Ling ZHAO Yan LIU Gao-Qiang and KUANG Si-Min |
| |
| Institution: | Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China;Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China;Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China;Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China |
| |
| Abstract: | The dynamic behavior of intracellular triterpene acids(ITA) and extracellular triterpene acids(ETA) of Ganoderma lucidum by batch fermentation in a 30L stirred tank bioreactor was observed.Unstructured kinetics of cell growth,glucose comsumption,ITA and ETA were investigated based on Sigmoid model.The parameters of the model were determined by Boltzmann simulation,and the values predicted by the models matched well with those obtained from the observed.The maximum rate for specific cell growth was found to ... |
| |
| Keywords: | medicinal fungus Ganoderma lucidum submerged fermentation triterpene acids kinetic model |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《菌物学报》浏览原始摘要信息 |
| 点击此处可从《菌物学报》下载免费的PDF全文 |
|
