Rodent-specific alternative exons are more frequent in rapidly evolving genes and in paralogs |
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| Authors: | Ramil N Nurtdinov Andrey A Mironov Mikhail S Gelfand |
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| Institution: | (1) Departament of Bioengineering and Bioinformatics, M.V. Lomonosov Moscow State University, Vorbyevy Gory 1-73, 119992 Moscow, Russia;(2) State Research Institute for Genetics and Selection of Industrial Microorganisms "GosNIIGenetika", 1st Dorozhny proezd 1, 117545 Moscow, Russia;(3) Institute for Information Transmission Problems, Russian Academy of Sciences, Bolshoi Karenty pereulok 19, 127994 Moscow, Russia |
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| Abstract: | Background Alternative splicing is an important mechanism for generating functional and evolutionary diversity of proteins in eukaryotes.
Here, we studied the frequency and functionality of recently gained, rodent-specific alternative exons. |
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