Genetic factors in the development of chronic kidney disease in patients with diabetes mellitus |
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Authors: | O. K. Vikulova A. V. Zheleznyakova N. O. Lebedeva A. G. Nikitin V. V. Nosikov M. V. Shestakova |
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Affiliation: | 1.Endocrinology Research Centre,Moscow,Russia;2.Sechenov First Moscow State Medical University,Moscow,Russia;3.Federal Research Clinical Center,Moscow,Russia |
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Abstract: | Patients with diabetes mellitus (DM) represent a risk group for developing chronic kidney disease (CKD), the terminal stages of which require renal replacement therapy. The study of genetic predisposition to CKD is of special significance from the perspective of the prediction and identification of risk groups at the preclinical stage. The present study is a review of the world literature on the genetics of CKD in diabetes and also includes data of our own studies. |
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