| 蛋白质晶体的物理性质及其鉴别方法研究进展 |
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| 引用本文： | 解旭卓,曹慧玲,鹿芹芹,陈瑞卿,郭云珠,周伯儒,尹大川. 蛋白质晶体的物理性质及其鉴别方法研究进展[J]. 生物技术通讯, 2013, 0(1): 134-138 |
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| 作者姓名： | 解旭卓 曹慧玲 鹿芹芹 陈瑞卿 郭云珠 周伯儒 尹大川 |
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| 作者单位： | 西北工业大学 生命学院空间生物实验模拟技术国防重点学科实验室,陕西 西安 710072 |
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| 基金项目： | 国家自然科学基金(31170816);国家高等学校博士学科点专项科研基金(20116102120052);西北工业大学研究生创业种子基金(Z2012195) |
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| 摘 要： | 蛋白质晶体由蛋白质分子有序排列的框架组成，其内部富含溶剂（水）分子，外观形貌多种多样，其物理性质与常规固态晶体相比有很大不同。我们针对蛋白质晶体的一些物理性质（包括低密度、机械性能、声学、热学、光学等性质），进行了研究进展评述，并根据蛋白质晶体的特殊物理性质，评述了人们发展出的从蛋白质结晶液中区分蛋白质晶体的方法。
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| 关 键 词： | 蛋白质晶体 物理性质 鉴别方法 |
Research Progresses in Physical Properties of Protein Crystals and Related Distinguishing Methods |
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| XIE Xu-Zhuo,CAO Hui-Ling,LU Qin-Qin,CHEN Rui-Qing,GUO Yun-Zhu,ZHOU Bo-Ru,YIN Da-Chuan. Research Progresses in Physical Properties of Protein Crystals and Related Distinguishing Methods[J]. Letters in Biotechnology, 2013, 0(1): 134-138 |
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| Authors: | XIE Xu-Zhuo CAO Hui-Ling LU Qin-Qin CHEN Rui-Qing GUO Yun-Zhu ZHOU Bo-Ru YIN Da-Chuan |
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| Affiliation: | Key Laboratory for Space Bioscience & Biotechnology,School of Life Sciences,Northwestern Polytechnical University,Xi’an 710072,China |
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| Abstract: | Protein crystals are well ordered frameworks assembled by protein molecules and full-filled with sol- vent（mainly water molecules）. The morphology of the crystals is of large variety and their physical properties are much different from those of the ordinary small molecular crystals. In this paper we reviewed the research progress- es in physical properties（including low-density, mechanical, acoustic, thermal, and optical properties） of protein crystals, and accordingly the methods for distinguishing between protein and salt crystals in the crystallization solu- tion were also included. |
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| Keywords: | protein crystal physical property distinguishing method |
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