Research in the field of imidazo[1,2-<Emphasis Type="Italic">a</Emphasis>]benzimidazole derivatives. XXX. Synthesis and properties of (imidazo[1,2-<Emphasis Type="Italic">a</Emphasis>]benzimidazolyl-2)acetic acids |
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| Authors: | V A Anisimova I E Tolpygin A A Spasov T S Serdyuk A G Sukhov |
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| Institution: | 1.Institute of Physical and Organic Chemistry,Southern Federal University,Rostov-on-Don,Russia;2.Volgograd State Medical University,Volgograd,Russia;3.Kogan Research Institute of Neurocybernetics,Southern Federal University,Rostov-on-Don,Russia |
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| Abstract: | Ethyl esters of (9-subtituted-imidazo1,2-a]benzimidazolyl-2)acetic acids have been synthesized. The chemical properties of these esters have been studied: hydrolysis,
decarboxylation, hydrazinolysis, and hydrazone formation. Some of these compounds demonstrate biological activity (fungicidal,
antimicrobial, antiarrhythmic) and effects on brain rhythmogenesis. |
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