Hepatitis B virus exposure in human immunodeficiency virus seropositive Cuban patients |
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Authors: | Rodríguez L Collado-Mesa F Aragón U Díaz B Rivero J |
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Institution: | Laboratorio de Referencia para Hepatitis Virales, Departamento de Virología, Instituto Pedro Kourí, Habana, 601, Cuba. licel@ipk.sld.cu |
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Abstract: | In order to estimate the prevalence of serological markers of exposure to Hepatitis B Virus (HBV), 295 subjects were selected at random from the National Registry of human immunodeficiency virus positive subjects. Evidence of exposure to HBV was defined as: testing Hepatitis B surface antigen (HBsAg) and anti-Hepatitis B core antigen (anti-HBc) positive or anti-HBc positive only. Overall, 133 (45.5%) were positive for anti-HBc and 15 (5.1%) resulted positive to HBsAg. Significant statistical association was found between male sex and exposure to HBV (p<0.01). Homosexual or bisexual behavior was found to be strongly associated to HBV exposure (p<0.001). In conclusion, the prevalence of HBV serological markers is higher in Cuban HIV positive subjects compared to the Cuban general population. |
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