The location of the genes coding for hexon and fiber proteins in adenovirus DNA. |
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| Authors: | V Mautner J Williams J Sambrook P A Sharp T Grodzicker |
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| Affiliation: | National Institute for Medical Research Mill Hill London NW7 1AA, England;MRC Virology Unit Institute of Virology Glasgow G11 5JR, Scotland;Cold Spring Harbor Laboratory Cold Spring Harbor, New York 11724 USA |
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| Abstract: | A serological analysis has been made of the capsid antigens hexon and fiber from 17 Ad5-Ad2+ND1 recombinants that enables us to determine the phenotype of the recombinants. By correlation of this data with the genetic and physical maps of the adenovirus genome, obtained by recombination and restriction endonuclease analysis, the genes coding for the hexon and fiber have been assigned to specific locations on the adenovirus DNA. |
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