The distribution of Concanavalin A binding sites on the intestinal epithelium of the nematodes Ascans suum and Parascaris equorum

Summary Receptors for Concanavalin A (Con A), were localized on the intestinal epithelium of the nematodes Ascaris suum and Parascaris equorum. Fixed tissue incubated in ³H-Con A showed labeling of the microvilli surface and basal membrane. Using Con A coupled with peroxidase, the tips of the microvilli of Ascaris suum and the tips and lateral surfaces of Parascaris equorum were stained. The basal membrane of both species was also labeled. No labeling was observed on control tissue incubated without Con A or on tissue incubated with Con A to which -methyl-D-mannoside was added.