Structural dynamic aspects of protein synthesis on ribosomes |
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| Authors: | A Spirin |
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| Affiliation: | Institute of Protein Research, Academy of Sciences of the U.S.S.R., Pushchino, Moscow Region. |
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| Abstract: | Three types of conformational changes in the translating ribosome are considered: (1) intersubunit movement (ribosome unlocking) during translocation; (2) L7/L12 stalk mobility affected by elongation factors; (3) change of tRNA residue during its transition from the A-site to the P-site. Relevant experimental data are reviewed. |
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