Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms |
| |
| Authors: | Dong Chen Zhiyong Chen Chanyoung Park Michael Centrella Thomas McCarthy Li Chen Ahmed Al-Omari Gilbert W. Moeckel |
| |
| Affiliation: | 1. Department of Pathology, Yale University School of Medicine, New Haven, USA;2. Department of Surgery, Yale University School of Medicine, New Haven, USA |
| |
| Abstract: | |
| |
| Keywords: | AP1, activator protein 1 ARB, angiotensin receptor blocker CKD, chronic kidney disease DMEM, Dulbecco's modified Eagle's medium EGFR, epidermal growth factor receptor ERK1/2, extracellular signal-regulated kinase FBS, fetal bovine serum GRE, glucocorticoid responsive element IgF1-R, insulin-like growth factor-1 JNK, c-Jun NH2-terminal protein kinase MCR, mineralocorticoid receptor MDCK, Madin&ndash Darby canine kidney epithelial cells MMTV, mouse mammary tumor virus Src, proto-oncogene tyrosine-protein kinase Src TGF-β, transforming growth factor beta PCNA, proliferating cell nuclear antigen PKC, protein kinase c VSMC, vascular smooth muscle cell |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
