Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient |
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| Authors: | Alvarado-Mora Mónica Viviana Santana Rúbia Anita Ferraz Sitnik Roberta Ferreira Paulo Roberto Abrão Mangueira Cristovão Luís Pitangueira Carrilho Flair José Pinho João Renato Rebello |
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| Affiliation: | Departamento de Gastroenterologia, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de S?o Paulo, S?o Paulo, SP, Brasil. monica.viviana@usp.br |
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| Abstract: | The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil. |
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