Nuclear inclusions in paraventricular nucleus neurons of the rat hypothalamus |
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Authors: | Dr Miguel Lafarga Gabriel Palacios |
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Institution: | (1) Department of Anatomy, Faculty of Medicine, Santande, Spain;(2) I.B.F., Autonomous University, Barcelona, Spain;(3) Departamento de Anatomia, Facultad de Medicina, Cazoña s/n, Santander, España |
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Abstract: | Summary This paper deals with the ultrastructure of two types of intranuclear inclusions, microfilamentous spindle-shaped and crystalloid, present in paraventricular nucleus neurons of adult normal rats. These inclusions appear occasionally in some non-secretory neurons of the parvocellular system, but have never been seen in neurosecretory cells of the magnocellular system. The microfilamentous spindle-shaped inclusions show a close spatial relationship with the granulofibrillar body and interchromatin granules.The distribution and functional significance of such structures are discussed in the light of recent ultrastructural and biochemical studies on nuclear inclusions. |
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Keywords: | Nuclear inclusions Neurons Paraventricular nucleus Hypothalamus Rat |
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