Variations in amount of TSST-1 produced by clinical methicillin resistant Staphylococcus aureus (MRSA) isolates and allelic variation in accessory gene regulator (agr) locus |
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| Authors: | Miki Nagao Akira Okamoto Keiko Yamada Tadao Hasegawa Yoshinori Hasegawa Michio Ohta |
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| Affiliation: | (1) Department of Infection Control and Prevention, Kyoto University Hospital, Kyoto, Japan;(2) Department of Molecular Bacteriology, Nagoya City University Graduate School of Medical Science, Nagoya, Japan;(3) Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan |
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| Abstract: | Background Staphylococcus aureus (S. aureus) is an important pathogen associated with both nosocomial and community-acquired infections and its pathogenicity is attributed to its potential to produce virulence factors. Since the amount of toxin produced is related to virulence, evaluating toxin production should be useful for controlling S. aureus infection. We previously found that some strains produce relatively large amounts of TSST-1; however, no reports have described the amount of TSST-1 produced by clinical isolates. |
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