Selection against spermatozoa with fragmented DNA after postovulatory mating depends on the type of damage |
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Authors: | Juan D Hourcade Miriam Pérez-Crespo Raúl Fernández-González Belén Pintado Alfonso Gutiérrez-Adán |
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Institution: | 1.Dpto. de Reproducción Animal y Conservación de Recursos Zoogenéticos,INIA,Madrid,Spain;2.Centro Nacional de Biotecnología,Madrid,Spain |
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Abstract: | Background Before ovulation, sperm-oviduct interaction mechanisms may act as checkpoint for the selection of fertilizing spermatozoa
in mammals. Postovulatory mating does not allow the sperm to attach to the oviduct, and spermatozoa may only undergo some
selection processes during the transport through the female reproductive tract and/or during the zona pellucida (ZP) binding/penetration. |
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