Abstract: | Oxidation of glucose to 2,5-diketogluconic acid by Erwinia herbicola was inhibited at 100% dissolved O2 tension (DOT) relative to air at 1 atm. Gluconic acid accumulation, however, increased under this condition. The negative influence of the high DOT is attributed to a 10-fold decrease in 2-ketogluconate dehydrogenase activity.The authors are with the Department of Biotechnology, Regional Research Laboratory, Canal Road, Jammu Tawi-180001, India |