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Inhibition of glucose oxidation in Erwinia herbicola by a high concentration of dissolved O2
Authors:N. Sharma  G. N. Qazi
Abstract:Oxidation of glucose to 2,5-diketogluconic acid by Erwinia herbicola was inhibited at 100% dissolved O2 tension (DOT) relative to air at 1 atm. Gluconic acid accumulation, however, increased under this condition. The negative influence of the high DOT is attributed to a 10-fold decrease in 2-ketogluconate dehydrogenase activity.The authors are with the Department of Biotechnology, Regional Research Laboratory, Canal Road, Jammu Tawi-180001, India
Keywords:Airlift reactor  2,5-diketogluconic acid  dissolved oxygen tension  Erwinia herbicola  NADP-independent dehydrogenases
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