Superoxide anion radical induces lipid phase transitions that mimic temperature-induced phase-transition phenomenon of membrane lipids |
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Authors: | G P Kumar N Tillo M Laloraya M Nivsarkar S Verma A Singh |
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Affiliation: | School of Life Sciences, Devi Ahilya Vishwavidyalaya, Indore, India. |
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Abstract: | A biological membrane is shown to undergo lipid-phase transition leading to increased membrane fluidity when exposed to extraneously generated superoxide anion radical. This phase-transition is several folds higher in magnitude when compared to the temperature-induced fluidity change at the transition temperatures. This finding could have significant importance since an altered membrane configuration may involve aspects of biochemistry, biophysics or physiology. |
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