不同海拔高度对健康成年男性心脏血流动力学和心电图的影响

目的:监测中国南极冰盖考察预选队员心血管系统随海拔增高的变化,探讨筛查低氧易感队员和急性高原病的防治。方法:用无创血流动力学监护仪和十二导联心电图机,在北京(40 m)、拉萨(3 650 m)、羊八井(4 300 m)对第25次和26次南极冰盖考察预选队员心血管功能进行连续动态性监测。结果:随着海拔的增高,心率、收缩压、舒张压、平均动脉压、外周血管阻力、外周血管阻力指数显著升高(P0.05),心输出量、心指数、搏出量、搏出指数、加速度指数、速度指数、左心射血时间显著降低(P0.05),预射血期呈降低趋势(P0.05)。结论:随着海拔的增高,预选队员的外周血管阻力显著升高,左心泵血和收缩功能减弱且与Q-TC间期呈负相关。

Effects of different altitudes on cardiac hemodynamics and electrocardiogram of healthy male adults

Objective: To detect the changes of cardiovascular system at different altitudes,so as to prevent and predict the susceptibility to acute mountain sickness.Methods: The test was performed with noninvasive cardiovascular monitor and electrocardiogram in healthy male Chinese members of the 25th and 26th expeditions to the antarctic kunlun station at different altitudes(40 m,3 650 m and 4 300 m).Results: Compared with 40 m,from 3 650 m to 4 300 m,heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial pressure(MAP),systemic vascular resistance(SVR),systemic vascular resistance index(SVRI) significantly increased(P<0.05);cardiac output(CO),cardiac index(CI),stroke volume(SV),stroke index(SI),velocity index(VI),acceleration index(ACI),left ventricular ejection time(LVET) significantly decreased(P<0.05) and pre-ejection period(PEP) decreased with no significance(P>0.05).Conclusion: SVR significantly increased but contractile and blood-pumping function of left ventricular decreased inversely associated with the Q-TC interval,as the altitude is increasing.