| 好氧活性污泥体系中磺胺类抗生素生物降解的研究进展 |
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| 引用本文： | 许航,朱思橙,张文辉,季荣.好氧活性污泥体系中磺胺类抗生素生物降解的研究进展[J].生物工程学报,2021,37(10):3459-3474. |
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| 作者姓名： | 许航 朱思橙 张文辉 季荣 |
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| 作者单位： | 1 南京大学 环境学院 污染控制与资源化研究国家重点实验室，江苏 南京 210023;1 南京大学 环境学院 污染控制与资源化研究国家重点实验室，江苏 南京 210023;2 南京大学泉州环保产业研究院，福建 泉州 362000 |
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| 基金项目： | 国家自然科学基金委员会欧盟合作研究项目 (No. 31861133003)，泉州市科技计划项目 (Nos. 2018CT006, 2020CT002) 资助。 |
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| 摘 要： | 磺胺类抗生素(Sulfonamides,SAs)是一类被广泛应用于医疗和畜禽养殖的抗菌药物,但其在人和动物肠道中的可降解性较差,会通过人及畜禽粪便和尿液的排放进入污水处理系统。目前,污水处理厂中的好氧活性污泥(Aerobic activated sludge,AAS)被证实能够有效转化SAs。文中基于对国内外文献的调研,总结了好氧活性污泥体系中SAs生物降解的研究进展,对生物降解机理、主要的生物降解途径和影响降解效率的环境因素进行了梳理与回顾,并针对现有研究的不足提出展望,以期为优化污水处理厂中SAs的生物降解提供科学依据。
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| 关 键 词： | 磺胺类抗生素，好氧活性污泥，生物降解机制，降解途径 |
| 收稿时间： | 2021/6/5 0:00:00 |
Advances in biodegradation of sulfonamides antibiotics in aerobic activated sludge system |
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| Hang Xu,Sicheng Zhu,Wenhui Zhang,Rong Ji.Advances in biodegradation of sulfonamides antibiotics in aerobic activated sludge system[J].Chinese Journal of Biotechnology,2021,37(10):3459-3474. |
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| Authors: | Hang Xu Sicheng Zhu Wenhui Zhang Rong Ji |
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| Institution: | 1 State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, Jiangsu, China;1 State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, Jiangsu, China;2 Quanzhou Institute for Environmental Protection Industry, Nanjing University, Quanzhou 362000, Fujian, China |
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| Abstract: | Sulfonamides (SAs) are a kind of antibiotics widely used in medical treatment and livestock breeding. However, they have poor degradability in human and animal intestines, and will enter the sewage treatment system through the discharge of feces and urine. The aerobic activated sludge (AAS) in wastewater treatment plant was found to be able to effectively transform SAs. This article summarizes the advances in biodegradation of SAs in aerobic activated sludge system, which includes the biodegradation mechanisms, the main biodegradation pathways, and the environmental factors affecting the degradation efficiency. Challenges encountered in the current research were discussed, with the aim to provide scientific basis for optimizing the biodegradation of SAs in wastewater treatment process. |
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| Keywords: | sulfonamide antibiotics aerobic activated sludge biodegradation mechanism degradation pathway |
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