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新型抗肺癌转移药系列化合物的合成
引用本文:刘春祥,杜东里,冉祥凯,林炳勇,宫莲珍,侯竹影. 新型抗肺癌转移药系列化合物的合成[J]. 氨基酸和生物资源, 1993, 0(4): 1-3
作者姓名:刘春祥  杜东里  冉祥凯  林炳勇  宫莲珍  侯竹影
作者单位:山东医科大学药学系,山东医科大学药学系,山东医科大学药学系,山东医科大学药学系,山东医科大学药学系,山东医科大学药学系 济南 250012,济南 250012,济南 250012,济南 250012,济南 250012,济南 250012
摘    要:本文以对氨基苯甲酸为原料,经过重氮化、偶合、成盐等反应,合成4个抗肺癌转移药,并作了红外鉴定。

关 键 词:4-(3,3—二甲基—1—三氮烯基)苯甲酸钾(DM—COOK)  抗肺癌转移药  合成  类似物

Synthesis Of A Series Of New Type Inhibitory Agents Of Pulmonary Tumor Metastases
Liu ChunXiang,Du DongLi,Ran XiangKi,Lin BixgYong,Gong LianZhen,Hou ZhuYing Departmlnt of pharmacology Shandong Medical University,Jinan. Synthesis Of A Series Of New Type Inhibitory Agents Of Pulmonary Tumor Metastases[J]. Amino Acids & Biotic Resources, 1993, 0(4): 1-3
Authors:Liu ChunXiang  Du DongLi  Ran XiangKi  Lin BixgYong  Gong LianZhen  Hou ZhuYing Departmlnt of pharmacology Shandong Medical University  Jinan
Affiliation:Liu ChunXiang,Du DongLi,Ran XiangKi,Lin BixgYong,Gong LianZhen,Hou ZhuYing Departmlnt of pharmacology Shandong Medical University,Jinan 250012
Abstract:This Kind of Compounds has been Known as a new effe-ctive inhibition agent of pulmonary metastases, which is exploiting in western countries, we improved the way of synthesis and got the com-pound of 4 - (3, 3 -Dimethyl- 1 -triazenyl) benzoic acid potassium salt (DM-COOK) as well as its analogue 4 - (3, 3 -Diethyl- 1 -Triazenyl) benzoic acid potassium salt.
Keywords:4—(3, 3—Diethyl—1—Triazenyl) benzoic acid Potassium Salt (DM—COOK)  inhibition agent of pulmonary metastaases  Synthesis  Analogues
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