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Selective separation and co-culture of cells by photo-induced enhancement of cell adhesion (PIECA) |
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| Authors: | Edahiro Jun-Ichi Sumaru Kimio Ooshima Yuki Kanamori Toshiyuki |
| Institution: | Research Center of Advanced Bionics, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan. |
| Abstract: | Taking advantage of the phenomenon that animal cells adhering to a culture substrate are temporarily immobilized by light irradiation, we established a technique to manipulate the cells adhering to a culture substrate under microscopic observation. Using this technique, we demonstrated a separation of cells adhering to a culture substrate and fabrication of an elaborately patterned co-culture system. |
| Keywords: | photo‐induced enhancement of cell adhesion cell photo‐manipulation cell patterning co‐culture system cell separation animal cells |
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