Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer |
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| Authors: | Decock J Obermajer N Vozelj S Hendrickx W Paridaens R Kos J |
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| Affiliation: | Laboratory for Experimental Oncology, K.U. Leuven, University Hospitals Leuven, Leuven - Belgium. julie.decock@med.kuleuven.be |
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| Abstract: | Numerous studies have linked cathepsins and their inhibitor cystatin C to tumor invasion and metastasis. We examined whether cathepsin B, cathepsin H, cathepsin X and cystatin C could be detected in sera from women with early stage or inflammatory breast cancer and whether they correlated with clinicopathological characteristics. Preoperative serum was obtained from 176 patients with early-stage breast cancer (tumor size
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