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L‐asparaginase isolated from Streptomyces ansochromogenes promotes Th1 profile and activates CD8+ T cells in human PBMC: an in vitro investigation |
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| Authors: | GR da Silva Lacerda CML de Melo AK de Araújo Soares LR Moreira MC Coriolano GM de Souza Lima TH Napoleão VMB de Lorena LA de Oliveira da Silva SC do Nascimento |
| Institution: | 1. Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil;2. Laboratory of Immunological and Antitumor Analyzes, Department of Antibiotics, Federal University of Pernambuco, Pernambuco, Brazil;3. Laboratory of Immunoparasitology – Aggeu Magalh?es Research Center (CPqAM), Oswaldo Cruz Foundation (FIOCRUZ), Pernambuco, Brazil;4. Laboratory of Glycoproteins – Department of Biochemistry, Federal University of Pernambuco, Pernambuco, Brazil |
| Abstract: | |
| Keywords: | acute lymphoblast leukaemia immunomodulation L‐asparaginase lymphocytes Streptomyces ansochromogenes |