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Genetically engineered insulin and its pharmaceutical analogues |
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| Authors: | D. A. Gusarov V. D. Gusarova D. I. Bayramashvili A. F. Mironov |
| Affiliation: | (1) Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Mikloukho-Maklaya 16/10, Moscow, 117997, Russia;(2) Lomonosov Moscow State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 119571, Russia |
| Abstract: | Studies of replacement therapy of diabetes mellitus resulted not only in introduction of series of forms of insulin available at pharmaceutical market but also in new insulin analogues, which exhibit better control of blood glucose level. The present paper deals with basic tendencies in this field. |
| Keywords: | genetically engineered human insulin diabetes mellitus insulin-aspart insulin-glargin insulin-detemir insulin-lyspro |
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