waveTM: wavelet-based transmembrane segment prediction |
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Authors: | Pashou Evanthia E Litou Zoi I Liakopoulos Theodore D Hamodrakas Stavros J |
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Affiliation: | Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece. |
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Abstract: | waveTM is a web tool for the prediction of transmembrane segments in alpha-helical membrane proteins. Prediction is performed by a dynamic programming algorithm on wavelet-denoised 'hydropathy' signals. Users submit a protein sequence and receive interactively the results. Topology prediction can also be obtained in conjunction with the algorithm OrienTM. A web server that implements the waveTM algorithm is freely available at http://bioinformatics.biol.uoa.gr/waveTM. |
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